CSF antibiotic prophylaxis for neurosurgical patients with ventriculostomy: a randomised study
Refereed conference paper presented and published in conference proceedings

香港中文大學研究人員

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摘要The value of prophylactic antibiotics for patients with ventricular catheter for monitoring and CSF drainage is uncertain. 228 patients were randomised to receive perioperative antibiotics only (Unasyn, Group I) or prolonged antibiotics for the presence of the ventricular catheter (Unasyn and Aztreonam, Group II). The incidence of intracranial and extracranial infection was documented prospectively. Group II patients had a significantly reduced incidence of CSF infection [3/115 (3%) vs 12/113 (11%), p = 0.01] and extracranial infections [23/115 (20%) vs 48/113 (42%), p = 0.002]. CSF pathogens in Group II patients were MRSA and Candida, whereas in Group I, Staphylococci, E coli and Klebsiella. Although prolonged antibiotic prophylaxis significantly reduced the incidence of serious CSF infection as well as extracranial infections, this policy did select resistant or opportunistic pathogens such as Candida and MRSA.
著者Poon WS, Ng S, Wai S
會議名稱10th International ICP Symposium
會議開始日25.05.1997
會議完結日29.05.1997
會議地點WILLIAMSBURG
會議國家/地區美國
期刊名稱Acta Neurochirurgica -Supplementum then Supplement- Wien-
詳細描述Paper presented in the 10th International Symposium on Intracranial Pressure and Neuromonitoring in Brain Injury.
出版年份1998
月份1
日期1
卷號71
出版社SPRINGER-VERLAG WIEN
頁次146 - 148
國際標準書號3-211-83094-4
國際標準期刊號0065-1419
語言英式英語
關鍵詞antibiotic prophylaxis; ventriculostomy
Web of Science 學科類別Clinical Neurology; Emergency Medicine; Neurosciences & Neurology

上次更新時間 2021-23-02 於 00:47