Differential localization of GABA(A) receptor alpha and beta subunits in the hamster retina and relationship with glutamic acid decarboxylase immunoreactivity
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香港中文大學研究人員

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摘要In order to determine the cellular localization of GABA(A) alpha and beta subunits in the hamster retina, single and double immunocytochemistry was performed in perfuse-fixed hamster retina using commercially-available antibodies against the two receptor subunits and glutamic acid decarboxylase. Strong GABA(A) beta immunoreactivity was found in two strata of the inner plexiform layer and in perikarya of amacrine cells and bipolar cells in the inner nuclear layer. In contrast, no GABA(A) alpha immunoreactivity was detected. All but a few of the GABA(A) beta-immunoreactive amacrine cells were found not to display glutamic acid decarboxylase immunoreactivity. The present results indicate that there is a differential localization of GABA(A) alpha and beta subunits in different neuronal subpopulations in the hamster retina. (C) 1998 Elsevier Science Ireland Ltd.
著者Lee YL, Cho EYP, Yung KKL
期刊名稱Neuroscience Letters
出版年份1998
月份5
日期22
卷號248
期次1
出版社ELSEVIER SCI IRELAND LTD
頁次29 - 32
國際標準期刊號0304-3940
電子國際標準期刊號1872-7972
語言英式英語
關鍵詞avidin-biotin-peroxidase reaction; GABA(A)alpha subunit; GABA(A)beta subunit; immunocytochemistry; immunofluorescence
Web of Science 學科類別Neurosciences; NEUROSCIENCES; Neurosciences & Neurology

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