CFTR gene and male fertility
Publication in refereed journal

香港中文大學研究人員

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摘要Secretion of electrolytes and water by the epididymal epithelium is important in the formation an optimal fluid environment for sperm maturation and transport. This process is disrupted in the genetic disease cystic fibrosis caused by mutation of the cystic fibrosis transmemebrane conductance regulator (CFTR) gene. Recent findings of CFTR gene mutations in healthy men with congenital bilateral absence of the vas deferens or poor sperm quality may indicate that CFTR gene mutations have a far-reaching effect on human reproduction.
著者Wong PYD
期刊名稱Molecular Human Reproduction
出版年份1998
月份2
日期1
卷號4
期次2
出版社OXFORD UNIV PRESS
頁次107 - 110
國際標準期刊號1360-9947
語言英式英語
關鍵詞CBAVD; CFTR; chloride secretion; cystic fibrosis; epididymis
Web of Science 學科類別Developmental Biology; DEVELOPMENTAL BIOLOGY; Obstetrics & Gynecology; Reproductive Biology; REPRODUCTIVE BIOLOGY

上次更新時間 2020-24-10 於 03:13