The aqueous extract of rhizome of Gastrodia elata Blume attenuates locomotor defect and inflammation after traumatic brain injury in rats
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AbstractEthnopharmacological relevance: Traumatic brain injury (TBI) has an incident rate of 200-300 people per 100,000 annually in the developed countries. TBI has relatively high incidence at an early age and may cause long-term physical disability. Patients suffered from severe TBI Would have motor and neuropsychological malfunctions, affecting their daily activities. Traditionally, Gastrodia elata Blume is a Chinese Medicines which was used for the head diseases, while their efficiency on reducing brain damage was still largely unknown. In the present study, we aimed to examine the effect of water extract of G. elate Blume (GE) against TBI and elucidate its underlying mechanism.
All Author(s) ListNg CF, Ko CH, Koon CM, Chin WC, Kwong HCST, Lo AWI, Wong HL, Fung KP, Lau CBS, Lam PK, Poon WS, Leung PC
Journal nameJournal of Ethnopharmacology
Volume Number185
Pages87 - 95
LanguagesEnglish-United Kingdom
KeywordsControlled cortical impact; Gastrodia elata Blume; Inflammation; Rotarod; Traumatic brain injury
Web of Science Subject CategoriesChemistry, Medicinal; Integrative & Complementary Medicine; Pharmacology & Pharmacy; Plant Sciences

Last updated on 2021-18-09 at 00:27