Effects of Gegen (Puerariae lobatae Radix) water extract on improving detrusor overactivity in spontaneously hypertensive rats
Publication in refereed journal


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摘要Aim: Ex vivo experiments showed that the water extract of Puerariae lobatae Radix (named Gegen in Chinese) induced detrusor relaxation. The aim of this study was to prove the in vivo efficacy of Gegen on improving detrusor overactivity and its possible synergism with darifenacin (a first-line muscarinic receptor-3 inhibitor) in spontaneously hypertensive rats (SHR), a rat model exhibiting symptoms of detrusor overactivity.
著者Zhou XL, Lam WP, Tang HC, Koon CM, Cheng L, Lau CBS, Liang W, Leung PC
期刊名稱Phytomedicine
出版年份2016
月份6
日期1
卷號23
期次6
出版社ELSEVIER GMBH, URBAN & FISCHER VERLAG
頁次672 - 678
國際標準期刊號0944-7113
電子國際標準期刊號1618-095X
語言英式英語
關鍵詞Darifenacin; Detrusor overactivity; Gegen; Puerariae lobatae Radix; Spontaneously hypertensive rat; Synergism
Web of Science 學科類別Chemistry, Medicinal; Integrative & Complementary Medicine; Pharmacology & Pharmacy; Plant Sciences

上次更新時間 2020-25-11 於 00:43