Comparison of the Early Clinical Outcomes between Combined Small-Incision Lenticule Extraction and Collagen Cross-Linking versus SMILE for Myopia
Publication in refereed journal


Times Cited
Web of Science12WOS source URL (as at 11/01/2021) Click here for the latest count
Altmetrics Information
.

Other information
AbstractBackground. To compare the early outcome of combined SMILE and collagen crosslinking (SMILE Xtra) with SMILE. Method. Prospective, comparative interventional study of 21 eyes receiving SMILE Xtra using a low energy protocol and 32 control eyes receiving SMILE only. The outcomes were compared at 1, 3, and 6 months postoperatively. Results. Both groups had myopia with spherical equivalent refraction (SEQ) > 4.00D. The SMILE Xtra group had thinner preoperative central corneal thickness and residual stromal bed thickness (p < 0.021). At 6 months, no eyes lost more than 1 line in corrected distance visual acuity. The safety index was 0.96 +/- 0.06 and 1.00 +/- 0.00 in SMILE Xtra and control, respectively (p < 0.001). 89% and 94% of eyes were within +/- 0.50 D of target refraction, respectively, with the mean error in SEQ correction being -0.17 +/- 0.26 D for SMILE Xtra and +0.03 +/- 0.25 D for control (p = 0.021). The efficacy index was 0.88 +/- 0.13 and 0.97 +/- 0.06, respectively (p = 0.005). Conclusion. SMILE Xtra had good overall safety profile and predictability at 6 months. However, when compared with control, the safety index and efficacy index were statistically significantly lower in the early postoperative period.
All Author(s) ListNg ALK, Chan TCY, Cheng GPM, Jhanji V, Ye C, Woo VCP, Lai JSM
Journal nameJournal of Ophthalmology
Detailed descriptionArticle ID 2672980.
Year2016
Month1
Day1
PublisherHINDAWI PUBLISHING CORP
ISSN2090-004X
eISSN2090-0058
LanguagesEnglish-United Kingdom
Web of Science Subject CategoriesMedicine, Research & Experimental; Ophthalmology; Research & Experimental Medicine

Last updated on 2021-12-01 at 00:47