A novel norovirus GII. 17 lineage contributed to adult gastroenteritis in Shanghai, China, during the winter of 2014-2015
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AbstractNorovirus (NoV) is now recognized as a leading cause of nonbacterial acute gastroenteritis; however, the NoV GII. 17 genotype has rarely been reported as the predominant genotype in clinical diarrhea cases. During the winter of 2014-2015, the GII. 17 genotype, together with the NoV GII.4 genotype, dominated in sporadic adult patients with gastroenteritis in Shanghai. Phylogenetic analysis based on full-length VP1 amino acid sequences showed that the GII. 17 strains that emerged in Shanghai have close evolutionary relationships with strains recently collected in the Hong Kong area, Guangdong province of China, and Japan during the same period. This cluster in the phylogenetic tree may represent a novel NoV GII. 17 lineage recently circulating in East Asia. Pairwise distances between clusters also revealed the evolution of the NoV GII. 17 genotype in previous decades. Our study emphasizes the importance of combined surveillance of NoV-associated infections.
All Author(s) ListChen HL, Qian FX, Xu J, Chan M, Shen Z, Zai SB, Shan ML, Cai JF, Zhang WJ, He J, Liu Y, Zhang J, Yuan ZH, Zhu ZQ, Hu YW
Journal nameEmerging Microbes and Infections
Volume Number4
LanguagesEnglish-United Kingdom
Keywordsgastroenteritis; genotypes; norovirus
Web of Science Subject CategoriesImmunology; Microbiology

Last updated on 2021-10-01 at 01:34