Childhood asthma is associated with polymorphic markers of PROC on 2q14 in addition to 17q21 locus
Publication in refereed journal


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摘要BackgroundChildhood asthma is caused by both genetic and environmental factors. The first genomewide association study (GWAS) for asthma revealed putative candidates on nine chromosomal regions in Caucasians, with 17q21 locus being the most widely replicated one. However, there was no replication study for the other loci. This study investigated genetic associations between childhood asthma and autosomal single nucleotide polymorphisms (SNPs) on eight loci reported in the first GWAS among Hong Kong Chinese.
著者Chan WC, Sy HY, Kong APS, Wong CK, Tse LY, Hon KL, Chan JCN, Wong GWK, Leung TF
期刊名稱Pediatric Allergy and Immunology
出版年份2015
月份3
日期1
卷號26
期次2
出版社WILEY-BLACKWELL
頁次173 - 180
國際標準期刊號0905-6157
電子國際標準期刊號1399-3038
語言英式英語
關鍵詞childhood asthma; chromosome 2q14; genetics; protein C; transcription factor binding
Web of Science 學科類別Allergy; Immunology; Pediatrics

上次更新時間 2020-24-11 於 23:57