Callus formation is related to the expression ratios of estrogen receptors-alpha and -beta in ovariectomy-induced osteoporotic fracture healing
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AbstractThis study characterizes ovariectomized (OVX)-induced osteoporotic fracture healing with focus on estrogen receptors (ERs). Callus formation plays a critical role in fracture healing, and ERs are well-known mechanosensors in osteogenic pathways. It was hypothesized that callus formation was related to and partially determined by the difference in expression patterns of ERs in both normal and OVX-induced osteoporotic fractures.
All Author(s) ListChow SK, Leung KS, Qin L, Wei FY, Cheung WH
Journal nameArchives of Orthopaedic and Trauma Surgery
Volume Number134
Issue Number10
Pages1405 - 1416
LanguagesEnglish-United Kingdom
KeywordsEstrogen receptors; Fracture healing; Osteoporosis
Web of Science Subject CategoriesOrthopedics; Surgery

Last updated on 2020-27-05 at 04:06