Asymmetric synthesis of 3,3,5,5-tetrasubstituted 1,2-dioxolanes: total synthesis of epiplakinic acid F
Publication in refereed journal

香港中文大學研究人員
替代計量分析
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其它資訊
摘要The first enantioselective total synthesis of epiplakinic acid F (1) was achieved through a pivotal step involving a radical-mediated asymmetric peroxidation of vinylcyclopropanes with molecular oxygen to construct highly substituted 1,2-dioxolanes. Subsequent conversions of the chiral 1,2-dioxolanes led to total synthesis of epiplakinic acid F (1) and the confirmation of its absolute configuration. The enantiomer of epiplakinic acid F methyl ester (2) was also prepared.
著者Tian XY, Han JW, Zhao Q, Wong HNC
期刊名稱Organic and Biomolecular Chemistry
出版年份2014
卷號12
期次22
出版社ROYAL SOC CHEMISTRY
頁次3686 - 3700
國際標準期刊號1477-0520
電子國際標準期刊號1477-0539
語言英式英語
Web of Science 學科類別Chemistry; Chemistry, Organic; CHEMISTRY, ORGANIC

上次更新時間 2020-24-10 於 02:24