Pathophysiological Roles and Clinical Importance of Biomarkers in Acute Coronary Syndrome
Publication in refereed journal


引用次數
替代計量分析
.

其它資訊
摘要Early diagnosis of acute coronary syndrome (ACS) is important to guide appropriate therapy at a time when it is most likely to be of value. Accurate prognostic and risk stratification will facilitate high-risk patients to have early advanced diagnostic investigations and early appropriate interventions in a cost-effective and efficient manner, while those patients at low risk of ACS complications do not need such costly diagnostic tests and unnecessary hospital admission. Recent investigations have demonstrated that elevation of biomarkers upstream from acute-phase biomarkers, biomarkers of plaque destabilization and rupture, biomarkers of myocardial ischemia, necrosis, and dysfunction may provide an earlier assessment of patient risk and identify patients with higher risk of having an adverse event. This review provides an overview of the pathophysiology and clinical characteristics of several well-established biomarkers as well as emerging biomarkers that may have potential clinical utility in patients with ACS. Such emerging biomarkers hold promise and need to be more thoroughly evaluated before utilization in routine clinical practice.
著者Chan CPY, Rainer TH
期刊名稱Advances in Clinical Chemistry
詳細描述ed. by Gregory S. Makowski.
出版年份2013
月份1
日期1
卷號59
出版社ELSEVIER ACADEMIC PRESS INC
頁次23 - 63
國際標準書號978-0-12-405211-6
國際標準期刊號0065-2423
語言英式英語
Web of Science 學科類別Medical Laboratory Technology

上次更新時間 2020-31-10 於 00:15