Radiotherapy for Nasopharyngeal Carcinoma and Combined Capecitabine and Nimotuzumab Treatment for Lung Metastases in a Liver Transplantation Recipient: A Case Experience of Sustained Complete Response
Publication in refereed journal

香港中文大學研究人員

引用次數
替代計量分析
.

其它資訊
摘要The primary treatment for nasopharyngeal carcinoma (NPC) is external beam radiotherapy. However, until now, there is little experience with the management of NPC occurred after solid organ transplantation. In this report, a 60-year-old man was found to have NPC (T2N1M0; stage III) 3 years after orthotopic liver transplantation treatment for hepatocellular carcinoma. Intensity-modulated radiotherapy (IMRT) was performed for NPC. One month after IMRT, complete response of NPC was achieved. However, multiple lung metastases occurred 18 months after the IMRT with the largest lesion measuring 4.1 x 5.5 cm and confirmed to be originated from NPC. Combined chemo-/targeted therapy consisted of capecitabine, and nimotuzumab was administered for four cycles. One month after initiation of capecitabine plus nimotuzumab treatment, a near-complete response was achieved for lung metastases. A repeat CT scan 1 year later showed sustained resolution of the lung metastases. The patient is still alive 16 months after the combined chemo-/targeted therapy.
著者Yan SX, Jiang X, Yang JS, Yan DF, Wang XJ
期刊名稱Cancer Biotherapy and Radiopharmaceuticals
出版年份2012
月份10
日期1
卷號27
期次8
出版社MARY ANN LIEBERT INC
頁次519 - 523
國際標準期刊號1084-9785
語言英式英語
關鍵詞capecitabine; de novo tumor; intensity-modulated radiotherapy; nasopharyngeal carcinoma; nimotuzumab; orthotopic liver transplantation
Web of Science 學科類別Medicine, Research & Experimental; MEDICINE, RESEARCH & EXPERIMENTAL; Oncology; ONCOLOGY; Pharmacology & Pharmacy; PHARMACOLOGY & PHARMACY; Radiology, Nuclear Medicine & Medical Imaging; RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING; Research & Experimental Medicine

上次更新時間 2021-01-03 於 00:07