The pharmacogenetics of beta-adrenergic receptor antagonists in the treatment of hypertension and heart failure
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AbstractIntroduction: beta-Blockers have an important therapeutic role throughout the cardiovascular continuum. However, there is considerable variation in response to these drugs, which may be related to genetic influences on their pharmacokinetics and pharmacodynamic effects.
All Author(s) ListChan SW, Hu M, Tomlinson B
Journal nameExpert Opinion on Drug Metabolism and Toxicology
Year2012
Month7
Day1
Volume Number8
Issue Number7
PublisherINFORMA HEALTHCARE
Pages767 - 790
ISSN1742-5255
eISSN1744-7607
LanguagesEnglish-United Kingdom
Keywordsbeta-adrenergic receptors; beta-blockers; cytochrome P450 2D6; heart failure; hypertension; pharmacogenetics
Web of Science Subject CategoriesBiochemistry & Molecular Biology; BIOCHEMISTRY & MOLECULAR BIOLOGY; Pharmacology & Pharmacy; PHARMACOLOGY & PHARMACY

Last updated on 2020-24-11 at 01:10