Systematic Identification of Spontaneous Preterm Birth-Associated RNA Transcripts in Maternal Plasma
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AbstractBackground: Spontaneous preterm birth (SPB, before 37 gestational weeks) is a major cause of perinatal mortality and morbidity, but its pathogenesis remains unclear. Studies on SPB have been hampered by the limited availability of markers for SPB in predelivery clinical samples that can be easily compared with gestational age-matched normal controls. We hypothesize that SPB involves aberrant placental RNA expression, and that such RNA transcripts can be detected in predelivery maternal plasma samples, which can be compared with gestational age-matched controls.
All Author(s) ListChim SSC, Lee WS, Ting YH, Chan OK, Lee SWY, Leung TY
Journal namePLoS ONE
Year2012
Month4
Day5
Volume Number7
Issue Number4
PublisherPUBLIC LIBRARY SCIENCE
ISSN1932-6203
LanguagesEnglish-United Kingdom
Web of Science Subject CategoriesMultidisciplinary Sciences; MULTIDISCIPLINARY SCIENCES; Science & Technology - Other Topics

Last updated on 2021-13-01 at 00:57