Unsymmetrical beta-cyclodextrin-conjugated silicon(IV) phthalocyanines as highly potent photosensitisers for photodynamic therapy
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摘要A series of unsymmetrical silicon(IV) phthalocyanines with a permethylated beta-cyclodextrin unit and a sugar or a diamino moiety as the axial substituents have been prepared. These compounds are highly photocytotoxic with IC50 values as low as 21 nM, which is ca. sevenfold lower than those of the symmetrical bis(cyclodextrin) analogue.
著者Lau JTF, Lo PC, Tsang YM, Fong WP, Ng DKP
期刊名稱Chemical Communications
出版年份2011
月份1
日期1
卷號47
期次34
出版社ROYAL SOC CHEMISTRY
頁次9657 - 9659
國際標準期刊號1359-7345
電子國際標準期刊號1364-548X
語言英式英語
Web of Science 學科類別Chemistry; Chemistry, Multidisciplinary; CHEMISTRY, MULTIDISCIPLINARY

上次更新時間 2020-20-10 於 02:20