An Intronic Variant in the GRP78, a Stress-Associated Gene, Improves Prediction for Liver Cirrhosis in Persistent HBV Carriers
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AbstractBackground: Our previous study indicated that a common variant (rs430397 G > A) in the intron 5 of glucose-regulated protein 78 (GRP78) gene was associated with risk and prognosis of primary hepatocellular carcinoma (HCC), including HBV and cirrhosis-related HCC. rs430397 polymorphism may be a contributing factor or biomarker of HBV infection or HBV-related cirrhosis.
All Author(s) ListZhu X, Chen LZ, Fan WG, Lin MCM, Tian LW, Wang M, Lin S, Wang ZF, Zhang JF, Wang JL, Yao H, Kung HF, Li DP
Journal namePLoS ONE
Year2011
Month7
Day14
Volume Number6
Issue Number7
PublisherPUBLIC LIBRARY SCIENCE
ISSN1932-6203
LanguagesEnglish-United Kingdom
Web of Science Subject CategoriesMultidisciplinary Sciences; MULTIDISCIPLINARY SCIENCES; Science & Technology - Other Topics

Last updated on 2021-19-10 at 23:53