Umbilical Cord-Derived Mesenchymal Stem Cells With Forced Expression of Hepatocyte Growth Factor Enhance Remyelination and Functional Recovery in a Rat Intracerebral Hemorrhage Model
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AbstractBACKGROUND: Spontaneous intracerebral hemorrhage (ICH) carries a high mortality rate, with survivors commonly left with permanent neurological deficits. Mesenchymal stem cell (MSC) transplantation promotes functional recovery in experimental ICH, and treatment with hepatocyte growth factor (HGF) is beneficial in ischemic stroke.
All Author(s) ListLiu AM, Lu G, Tsang KS, Li G, Wu Y, Huang ZS, Ng HK, Kung HF, Poon WS
Journal nameNeurosurgery
Volume Number67
Issue Number2
Pages357 - 365
LanguagesEnglish-United Kingdom
KeywordsHepatocyte growth factor; Intracerebral hemorrhage; Mesenchymal stem cells; Regeneration; Remyelination; Transduction; Umbilical cord
Web of Science Subject CategoriesClinical Neurology; CLINICAL NEUROLOGY; Neurosciences & Neurology; Surgery; SURGERY

Last updated on 2021-10-05 at 03:31