15-Lipoxygenases and its metabolites 15(S)-HETE and 13(S)-HODE in the development of non-small cell lung cancer
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摘要Background 15-S-Hydroxyeicosatetraenoic acid (15(S)-HETE) and 13-S-hydroxyoctadecadienoic acid (13(S)-HODE), both of which are metabolites of 15-lipoxygenases (15-LOXs), are endogenous ligands for peroxisome proliferator-activated receptor gamma (PPAR gamma). The activation of PPAR gamma inhibits cell growth and induces apoptosis in some cancers. The role of 15(S)-HETE) and 13(S)-HODE in the development of lung cancer is not clear.
著者Yuan HL, Li MY, Ma LT, Hsin MKY, Mok TSK, Underwood MJ, Chen GG
期刊名稱Thorax
出版年份2010
月份4
日期1
卷號65
期次4
出版社B M J PUBLISHING GROUP
頁次321 - 326
國際標準期刊號0040-6376
電子國際標準期刊號1468-3296
語言英式英語
Web of Science 學科類別Respiratory System; RESPIRATORY SYSTEM

上次更新時間 2020-11-09 於 01:45