Full Genome Analysis of an Emerging Cluster of Human Immunodeficiency Virus Type 1 Subtype B Infection in Hong Kong
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AbstractWith considerable capacity for genetic diversification, new HIV-1 genotypes have been reported over the years. Three HIV-1 isolates previously genotyped as B using gag and env sequences were completely sequenced and reanalyzed. Several amino acid mutations were found in vif, rev, and nef genes but not in gag or env sequences. These alterations have not previously been reported in Hong Kong. The investigation of phylogenetic relatedness revealed that a region of the vif of the studied Hong Kong isolates subtype B cluster contains several subtype D signature amino acid residues. Several unique mutations on vif in these three isolates were also identified.
All Author(s) ListTsui SKW, Fong NY, Li SK, Leung KK, Chan DPC, Chan PKS, Wong KH, Lee SS
Journal nameAIDS Research and Human Retroviruses
Year2010
Month1
Day1
Volume Number26
Issue Number1
PublisherMARY ANN LIEBERT INC
Pages117 - 122
ISSN0889-2229
eISSN1931-8405
LanguagesEnglish-United Kingdom
Web of Science Subject CategoriesImmunology; IMMUNOLOGY; Infectious Diseases; INFECTIOUS DISEASES; Virology; VIROLOGY

Last updated on 2020-04-08 at 06:14