The Effect of Volume of Chorionic Villi on Long-Term Cell Culture
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AbstractObjective: It was the aim of our study to investigate the association between culture time and weight of villi obtained by transabdominal chorionic villus sampling (CVS). Methods: We analyzed 1,442 villus samples. Results: The gestational age at sampling ranged from 10 to 14 weeks. The weight of villi in these samples ranged from 1 to 80 mg (median 10 mg, interquatile range 7 - 12 mg). The culture time ranged from 5 to 24 days. Culture time was significantly and inversely correlated with the weight of villi obtained (r = - 0.258, p<0.01). Time was significantly longer when 5 mg or less of villi was obtained but the difference was only up to 2 days. Conclusions: Because the difference in culture time for different groups of villus samples was within 1 - 2 days, this relationship is statistically significant but has no clinical significance. Copyright (C) 2008 S. Karger AG, Basel
All Author(s) ListChen M, Ng L, Lau E, Lee CP, Tang MHY, Lam YH
Journal nameFetal Diagnosis and Therapy
Volume Number24
Issue Number4
Pages409 - 412
LanguagesEnglish-United Kingdom
KeywordsCell culture techniques; Chorionic villi sampling; Chromosome aberrations; Karyotyping
Web of Science Subject CategoriesObstetrics & Gynecology; OBSTETRICS & GYNECOLOGY

Last updated on 2020-07-07 at 01:56