WNT5A exhibits tumor-suppressive activity through antagonizing the Wnt/beta-catenin signaling, and is frequently methylated in colorectal cancer
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摘要Purpose: Aberrant activation of theWnt/beta-catenin signaling pathway is associated with multiple tumors including colorectal cancer (CRC). WNT5A is a member of the nontransforming Wnt protein family, whose role in tumorigenesis is still ambiguous. We investigated its epigenetic alteration in CRCs.
著者Ying JM, Li HY, Yu J, Ng KM, Poon FF, Wong SCC, Chan ATC, Sung JJY, Tao Q
期刊名稱Clinical Cancer Research
出版年份2008
月份1
日期1
卷號14
期次1
出版社AMER ASSOC CANCER RESEARCH
頁次55 - 61
國際標準期刊號1078-0432
電子國際標準期刊號1557-3265
語言英式英語
Web of Science 學科類別Oncology; ONCOLOGY

上次更新時間 2020-27-11 於 01:36