Ginsenoside Rb1 inhibits tube-like structure formation of endothelial cells by regulating pigment epithelium-derived factor through the oestrogen beta receptor
Publication in refereed journal

香港中文大學研究人員

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摘要Background and purpose: Angiogenesis is a crucial step in tumour growth and metastasis. Ginsenoside-Rb1 ( Rb1), the major active constituent of ginseng, potently inhibits angiogenesis in vivo and in vitro. However, the underlying mechanism remains unknown. We hypothesized that the potent anti-angiogenic protein, pigment epithelium-derived factor ( PEDF), is involved in regulating the anti-angiogenic effects of Rb1.
著者Leung KW, Cheung LWT, Pon YL, Wong RNS, Mak NK, Fan TPD, Au SCL, Tombran-Tink J, Wong AST
期刊名稱British Journal of Pharmacology
出版年份2007
月份9
日期1
卷號152
期次2
出版社NATURE PUBLISHING GROUP
頁次207 - 215
國際標準期刊號0007-1188
電子國際標準期刊號1476-5381
語言英式英語
關鍵詞angiogenesis; endothelial cells; ginseng; oestrogen receptor; PEDF
Web of Science 學科類別Pharmacology & Pharmacy; PHARMACOLOGY & PHARMACY

上次更新時間 2021-12-04 於 00:04