Corticosteroids are not present in a traditional Chinese medicine formulation for atopic dermatitis in children
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AbstractIntroduction: Traditional Chinese medicine (TCM) has been used as an alternative in treating children with atopic dermatitis (AD) but its efficacy and potential side effects are debatable. We recently used a TCM capsule (PentaHerbs) on 9 children and observed significant reductions in clinical scores of disease severity. However, there have been concerns that the therapeutic effects of many forms of TCM are due to the presence of corticosteroids. The purpose of this study was to evaluate if common corticosteroids are present in PentaHerbs capsules. Materials and Methods: PentaHerbs powder was analysed with thin-layer chromatography, infra-red spectrophotometry and liquid chromatography mass spectrometry. Results: Hydrocortisone, prednisolone, fludrocortisone and dexamethasone were not detected in the PentaHerbs capsules. Conclusion: Corticosteroids are not present in the 5 familiar herbs that were earlier shown to have efficacy on AD.
All Author(s) ListHon KLE, Lee VWY, Leung TF, Lee KKC, Chan AKW, Fok TF, Leung PC
Journal nameAnnals of the Academy of Medicine, Singapore
Volume Number35
Issue Number11
Pages759 - 763
LanguagesEnglish-United Kingdom
Keywordsatopic dermatitis; corticosteroids; traditional Chinese medicine
Web of Science Subject CategoriesGeneral & Internal Medicine; Medicine, General & Internal; MEDICINE, GENERAL & INTERNAL

Last updated on 2021-11-05 at 01:16