Hypermethylated RASSF1A in maternal plasma: A universal fetal DNA marker that improves the reliability of noninvasive prenatal diagnosis
Publication in refereed journal


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其它資訊
摘要Background: We recently demonstrated that the promoter of the RASSF1A gene is hypermethylated in the placenta and hypomethylated in maternal blood cells. This methylation pattern allows the use of methylation-sensitive restriction enzyme digestion for detecting the placental-derived hypermethylated RASSF1A sequences in maternal plasma.
著者Chan KCA, Ding CM, Gerovassili A, Yeung SW, Chiu RWK, Leung TN, Lau TK, Chim SSC, Chung GTY, Nicolaides KH, Lo YMD
期刊名稱Clinical Chemistry
出版年份2006
月份12
日期1
卷號52
期次12
出版社AMER ASSOC CLINICAL CHEMISTRY
頁次2211 - 2218
國際標準期刊號0009-9147
電子國際標準期刊號1530-8561
語言英式英語
Web of Science 學科類別Medical Laboratory Technology; MEDICAL LABORATORY TECHNOLOGY

上次更新時間 2020-23-10 於 00:22