In vitro antiviral activities of Chinese medicinal herbs against duck hepatitis B virus
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AbstractFifty-six different Chinese medicinal herbs from 29 families were evaluated for their antiviral activities against duck hepatitis B virus (DHBV) in vitro. The DHBV DNA level in primary duck hepatocyte cultures was monitored by dot blot hybridization and the cytotoxicity was evaluated by MTT assay. Anti-DHBV activities were found more strongly in the aqueous extracts of Ardisia chinensis and Pithecellobium clypearia with selective indices of 2.6 and > 2.7, respectively, which were comparable to that of 2',3'-dideoxycytidine. Further research on the isolation of the active antiviral phytochemicals from these herbs may provide alternative options for the treatment of chronic hepatitis B. Copyright (c) 2006 John Wiley & Sons, Ltd.
All Author(s) ListLeung KT, Chiu LCM, Lam WS, Li YL, Sun SSM, Ooi VEC
Journal namePhytotherapy Research
Year2006
Month10
Day1
Volume Number20
Issue Number10
PublisherJOHN WILEY & SONS LTD
Pages911 - 914
ISSN0951-418X
eISSN1099-1573
LanguagesEnglish-United Kingdom
Keywordsantiviral; Chinese medicinal herbs; duck hepatitis B virus
Web of Science Subject CategoriesChemistry, Medicinal; CHEMISTRY, MEDICINAL; Pharmacology & Pharmacy; PHARMACOLOGY & PHARMACY

Last updated on 2020-12-07 at 03:28