Exhaled nitric oxide levels are not correlated with eczema severity in Chinese children with atopic dermatitis
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AbstractAsthma is a common atopic disease associated with atopic dermatitis (AD) and allergic rhinitis (AR). Exhaled nitric oxide level (eNO) has been found to be an interesting noninvasive marker of disease severity in children with asthma. However, it is uncertain if eNO may be confounded by any coexisting AD or AR. In this study, eNO in Chinese children with moderate-to-severe AD and no asthma symptoms (n = 53) was measured online by a chemiluminescence analyzer. Severity of AD was assessed using the objective SCORing-Atopic-Dermatitis score and coexisting allergic rhinitis with the Allergic-Rhinitis-Score (ARS). Patients with active symptoms of asthma or inhaled/intranasal corticosteroids were excluded. There was no difference in eNO between genders and no correlation between eNO and AD severity regardless of ARS or bronchial reactivity status. ENO appears to be a noninvasive marker whose level is independent of the two atopic diseases of AD and AR in children old enough to perform exhalation maneuver.
All Author(s) ListHon KLE, Leung TF, Kam WYC, Lam MCA, Wong KY, Yung E, Fok TF
Journal nameJournal of Asthma
Volume Number43
Issue Number6
Pages417 - 419
LanguagesEnglish-United Kingdom
Keywordsatopic dermatitis; children; exhaled nitric oxide; SCORAD
Web of Science Subject CategoriesAllergy; ALLERGY; Respiratory System; RESPIRATORY SYSTEM

Last updated on 2021-10-05 at 02:47