Rhinitis symptom utility index (RSUI) in Chinese subjects: A multiattribute patient-preference approach
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AbstractBackground: The Rhinitis Symptom Utility Index (RSUI), originally developed in the United States, consists of a patient-preference weighting scheme and a 10-item questionnaire measuring the severity and frequency of rhinitis related symptoms over a 14-day period. This study aimed to determine whether the Chinese RSUI could adopt the US-based multi-attribute utility function (MAUF) in scoring rhinitis symptoms. Methods: In a Hong Kong study, 116 Chinese adults with allergic rhinitis completed the RSUI questionnaire and 36-item Short-Form Health Survey (SF-36) after they had been seen by two otorhinolaryngologists for disease-severity ratings. Respondents then completed computer-administered direct preference measures, i.e., visual analogue scale (VAS) and standard gamble (SG) assessments. The VAS and SG data were used to estimate a MAUF for the Chinese-based RSUI. Results: The derived MAUF was somewhat different than the one developed for the US RSUI. Test-retest reliability for the Chinese RSUI was satisfactory (ICC = 0.71, p < 0.001). Scores differentiated among cases with mild, moderate, and severe symptoms (p < 0.001); and between those who did and did not require medications to control symptoms (p = 0.031). Findings were significantly correlated with SF-36 domain scores (r = 0.19 to 0.37; p = 0.041 to < 0.001). When the US- based scoring function was applied to the Chinese subjects, the resulting mean RSUI score was significantly lower (p < 0.001). Comparisons between directly measured VAS and SG scores between the US and Chinese samples, demonstrated significant differences (all p < 0.05), with the US subjects consistently rating rhinitis symptoms as worse than Chinese subjects. Conclusions: The Chinese RSUI has good measurement properties that reflect patient preferences from the Chinese. Results suggest that there are differences in preference rating between US and Chinese subjects and that use of the US-based preference function for the RSUI would bias the measurement of rhinitis symptom outcomes in Chinese subjects.
All Author(s) ListLo PSY, Tong MCF, Revicki DA, Lee CC, Woo JKS, Lam HCK, van Hasselt CA
Journal nameQuality of Life Research
Volume Number15
Issue Number5
Pages877 - 887
LanguagesEnglish-United Kingdom
Keywordshealth utility measurement; patient preference; rhinitis symptom utility index; standard gamble
Web of Science Subject CategoriesHealth Care Sciences & Services; HEALTH CARE SCIENCES & SERVICES; Health Policy & Services; HEALTH POLICY & SERVICES; Public, Environmental & Occupational Health; PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH, SCI; PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH, SSCI

Last updated on 2020-26-05 at 00:41