Expression of maspin in gestational trophoblastic disease
Publication in refereed journal


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摘要Background. Maspin is a tumor suppressor gene whose expression is altered in neoplasia and malignancies of many tissues. In the human placenta, the maspin gene is expressed in trophoblastic cells and might act as an inhibitory regulator of trophoblastic invasion. Hence, in gestational trophoblastic disease (GTD), where there is increased propensity for invasion in the trophoblastic tissue, we hypothesized that maspin expression would be decreased. The present study aimed at investigating the expression of maspin in GTD and its prognostic significance.
著者Li HWR, Leung SW, Cheung ANY, Yu MMY, Chan LKY, Wong YF
期刊名稱Gynecologic Oncology
出版年份2006
月份4
日期1
卷號101
期次1
出版社ACADEMIC PRESS INC ELSEVIER SCIENCE
頁次76 - 81
國際標準期刊號0090-8258
電子國際標準期刊號1095-6859
語言英式英語
關鍵詞choriocarcinoma; gestational trophoblastic disease; gestational trophoblastic neoplasia; hydatidiform mole; maspin; placental site trophoblastic tumor
Web of Science 學科類別Obstetrics & Gynecology; OBSTETRICS & GYNECOLOGY; Oncology; ONCOLOGY

上次更新時間 2020-14-11 於 01:01