Towards automating micro cellular detection process using micro vortex pump arrays
Refereed conference paper presented and published in conference proceedings

香港中文大學研究人員

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摘要This paper reports a polymer based microfluidic analysis system integrated with a surface plasmon resonance (SPR) biosensor for detecting the specific binding of biomolecules and qualitatively monitoring of cell adhesion on the sensor surface. Micropumps, microchannels, and SPR biosensor were integrated into a single polymer (PMMA) based microfluidic system. The integrated system has been studied in its potential application in bio-molecules detection and drug discovery. Two experiments, 1) monitoring the reaction between BSA-BSA antibody, and 2) monitoring the activities of living cells in the presence or absence of trypsin in RPMI-1640 medium, were conducted to show the feasibility of real-time cellular and molecular detection. Based on these successful experimental results we have also developed a computer-controllable vortex micropump system that will eventually automate many bio-molecular detection and drug discovery processes.
著者Lam RHW, Lei KF, Miao L, Dong ZL, Law WC, Suen YK, Li WJ, Ho AHP, Kong SK
會議名稱IEEE/ASME International Conference on Advanced Intelligent Mechatronics
會議開始日24.07.2005
會議完結日28.07.2005
會議地點Monterey
會議國家/地區美國
出版年份2005
月份1
日期1
出版社IEEE
頁次66 - 71
國際標準書號0-7803-9046-6
國際標準期刊號2159-6255
語言英式英語
Web of Science 學科類別Automation & Control Systems; Computer Science; Computer Science, Artificial Intelligence; Engineering; Engineering, Electrical & Electronic; Engineering, Mechanical; Robotics

上次更新時間 2020-26-11 於 01:36