Absence of association between angiotensin converting enzyme polymorphism and development of adult respiratory distress syndrome in patients with severe acute respiratory syndrome: a case control study
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摘要Background: It has been postulated that genetic predisposition may influence the susceptibility to SARS-coronavirus infection and disease outcomes. A recent study has suggested that the deletion allele ( D allele) of the angiotensin converting enzyme ( ACE) gene is associated with hypoxemia in SARS patients. Moreover, the ACE D allele has been shown to be more prevalent in patients suffering from adult respiratory distress syndrome ( ARDS) in a previous study. Thus, we have investigated the association between ACE insertion/deletion (I/D) polymorphism and the progression to ARDS or requirement of intensive care in SARS patients.
著者Chan KCA, Tang NLS, Hui DSC, Chung GTY, Wu AKL, Chim SSC, Chiu RWK, Lee N, Choi KW, Sung YM, Chan PKS, Tong YK, Lai ST, Yu WC, Tsang O, Lo YMD
期刊名稱BMC Infectious Diseases
出版年份2005
月份4
日期9
卷號5
出版社BIOMED CENTRAL LTD
國際標準期刊號1471-2334
語言英式英語
Web of Science 學科類別Infectious Diseases; INFECTIOUS DISEASES

上次更新時間 2020-13-07 於 02:04