Antibodies to guanosine triphosphate misidentified as anti-double-stranded DNA antibodies in a patient with antinuclear antibody-negative lupus, due to buckling of insolubilized assay DNA
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AbstractObjective. To investigate why the serum of a pediatric patient with systemic lupus erythematosus was persistently (>30 months) and strongly positive for antibodies to double-stranded DNA (dsDNA) as revealed by enzyme-linked immunosorbent assay (ELISA), but yielded negative results on the antinuclear antibody test (HEp-2 immunofluorescence [IF]).
All Author(s) ListMa CH, Hui J, Tang JTY, Leung DTM, Chui YL, Fok TF, Lim PL
Journal nameArthritis and Rheumatism
Volume Number50
Issue Number5
Pages1533 - 1538
LanguagesEnglish-United Kingdom
Web of Science Subject CategoriesRheumatology; RHEUMATOLOGY

Last updated on 2020-24-09 at 00:52