Anti-inflammatory effects of exendin-4, a glucagon-like peptide-1 analog, on human peripheral lymphocytes in patients with type 2 diabetes
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AbstractAims/Introduction: Type 2 diabetes is characterized by dysregulation of immunity, oxidative stress and reduced incretin effects. Experimental studies suggest that glucagon-like peptide (GLP-1) might have immunomodulating effects. We hypothesize that GLP-1 receptor agonist, exendin-4, might reduce inflammatory response in type 2 diabetes.
All Author(s) ListHe L, Wong CK, Cheung KKT, Yau HC, Fu A, Zhao HL, Leung KML, Kong APS, Wong GWK, Chan PKS, Xu G, Chan JCN
Journal nameJournal of Diabetes Investigation
Volume Number4
Issue Number4
Pages382 - 392
LanguagesEnglish-United Kingdom
KeywordsDiabetes; Exendin-4; Inflammation
Web of Science Subject CategoriesEndocrinology & Metabolism; ENDOCRINOLOGY & METABOLISM

Last updated on 2021-14-06 at 00:23