Alns: a new searchable and filterable sequence alignment format
Publication in refereed journal


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其它資訊
摘要Nucleotides and amino acids are basic building units of RNA, DNA and protein. Although intensive studies on understanding how changes in these building blocks affect the phenotypes of these biopolymers are ever increasing, many popular alignment formats are generated by pair-wise comparison tools such as the Basic Local Alignment Search Tool (BLAST). These alignments are user-friendly to researchers but are not convenient for searching, filtering and storage, in particular when there are thousands of alignments generated from highly conserved sequences. Here, we introduce a new alignment format, alns, to facilitate rapid and convenient association of genetic changes and similarity to other sources of information such as phenotypes, disease state, time, geography and taxonomy via simple spreadsheet functions. The format shall assist biologists from a wide range of disciplines in knowledge discovery.
著者Leung RKK, Tsui SKW
期刊名稱International Journal of Data Mining and Bioinformatics
詳細描述To ORKTS: DOI: 10.1504/IJDMB.2013.053193
出版年份2013
月份1
日期1
卷號7
期次2
出版社INDERSCIENCE ENTERPRISES LTD
頁次135 - 145
國際標準期刊號1748-5673
電子國際標準期刊號1748-5681
語言英式英語
關鍵詞alns; bioinformatics; sequence alignment format
Web of Science 學科類別Mathematical & Computational Biology; MATHEMATICAL & COMPUTATIONAL BIOLOGY

上次更新時間 2020-03-07 於 03:34