Aberrant Promoter Methylation of DLEC1, a Critical 3p22 Tumor Suppressor for Renal Cell Carcinoma, is Associated With More Advanced Tumor Stage
Publication in refereed journal

香港中文大學研究人員

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其它資訊
摘要Purpose: Identifying tumor suppressor genes silenced by promoter CpG methylation uncovers mechanisms of tumorigenesis and identifies new epigenetic biomarkers for early cancer detection. DLEC1 is located at 3p22.3, a critical tumor suppressor gene locus for renal cell carcinoma. We explored its epigenetic alteration in renal cell carcinoma and possible clinicopathological association.
著者Zhang QA, Ying JM, Li JS, Fan YC, Poon FF, Ng KM, Tao QA, Jin J
期刊名稱The Journal of Urology
出版年份2010
月份8
日期1
卷號184
期次2
出版社ELSEVIER SCIENCE INC
頁次731 - 737
國際標準期刊號0022-5347
電子國際標準期刊號1527-3792
語言英式英語
關鍵詞carcinoma, renal cell; DLEC1 (deleted in lung cancer) protein, human; genes, tumor suppressor; kidney; methylation
Web of Science 學科類別Urology & Nephrology; UROLOGY & NEPHROLOGY

上次更新時間 2020-25-09 於 13:09