Prevalence of Integrons in Antibiotic-Resistant Salmonella spp. in Hong Kong
Publication in refereed journal

香港中文大學研究人員

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摘要Of the 834 Salmonella spp. isolates collected from 2002 to 2004 in the New Territories East Cluster hospitals in Hong Kong, 21% were resistant to 3-14 antibiotics and 30% were resistant to nalidixic acid with reduced susceptibility to ciprofloxacin. A class 1 integron was present in 105 (13%) isolates, of which more than 50% were Salmonella Typhimurium. Class 2 or 3 integrons were not detected in any of the isolates. DNA sequencing showed that there were 16 different integrons, of which the most common, detected in 40% of isolates, was dfrA12-orfF-aadA2. Almost half of the isolates had lost the gacE Delta 1-sulI 3' conserved segment (3'CS). Four isolates had an orf513 gene downstream of the 3'CS. There was probably one predominant clone among each heterogeneous population of integron-harboring S. Typhimurium, S. Virchow, and S. Derby isolates in our community. This is the first thorough study of the prevalence and characteristics of integrons in Salmonella isolates in Hong Kong and the first to report a class I integron in S. Birkenhead, S. Landwasser, S. Litchfield, and S. Reading.
著者Jin YJ, Ling JM
期刊名稱Japanese Journal of Infectious Diseases
出版年份2009
月份11
日期1
卷號62
期次6
出版社Institute of Infectious Diseases
頁次432 - 439
國際標準期刊號1344-6304
電子國際標準期刊號1884-2836
語言英式英語
Web of Science 學科類別Infectious Diseases; INFECTIOUS DISEASES

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