Validation of prediction equations for estimating resting energy expenditure in obese Chinese children
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摘要Objectives: (1) To examine the validity of existing prediction equations (PREE) for estimating resting energy expenditure (REE) in obese Chinese children, (2) to correlate the measured REE (MREE) with anthropometric and biochemical parameters and (3) to derive a new PREE for local use. Design: Cross-sectional study. Subjects: 100 obese children (71 boys) were studied. Measurements: All subjects underwent physical examination and anthropometric measurement. Upper and central body fat distribution was signified by centrality and conicity index respectively, and REE was measured by indirect calorimetry. Fat free mass (FFM) were measured by DEXA scan. Thirteen existing prediction equations for estimating REE were compared with MREE among these obese children. Fasting blood for glucose, lipid profile and insulin were obtained. Results: The overall, male and female median MREEs were 7.1 mJ/d (IR 6.2-8.4), 7.3 mJ/d (IR 6.3-9.7) and 6.9 mJ/d (IR 5.6-8.1) respectively. No sex difference was noted in MREE (p=0.203). Most of the equations except Schofield equation underestimated REE of our children. By multiple linear regression, MREE was positively correlated with FFM (p<0.0001), conicity index (p<0.001) and centrality index (p=0.001). A new equation for estimating REE for local use was derived as: REE = (17.4*logFFM) + (11.4*conicity index) - (2.4*centrality index) - 31.3. The mean difference of new PREE-MREE was -0.011 mJ/d (SD 1.51) with an interclass correlation coefficient of 0.91. Conclusion: None of the existing prediction equations were accurate in their estimation of REE, when applied to obese Chinese children. A new prediction equation has been derived for local use.
著者Chan DFY, Li AM, Chan MHM, So HK, Chan IHS, Yin JAT, Lam CWK, Fok TF, Nelson EAS
期刊名稱Asia Pacific Journal of Clinical Nutrition
出版年份2009
月份1
日期1
卷號18
期次2
出版社H E C PRESS, HEALTHY EATING CLUB PTY LTD
頁次251 - 256
國際標準期刊號0964-7058
語言英式英語
關鍵詞body fat distribution; children; insulin resistance; obese; resting energy expenditure
Web of Science 學科類別Nutrition & Dietetics; NUTRITION & DIETETICS

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