GlnR positively regulates nasA transcription in Streptomyces coelicolor
Publication in refereed journal

香港中文大學研究人員

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摘要The model actinomycete, Streptomyces coelicolor is able to grow with nitrate as the sole nitrogen source. In this study, an assimilatory nitrate reductase encoding gene, nasA (SCO2473) was, for the first time, identified from the genome of S. coelicolor by genetic and physiological means. We also proved that GlnR, a previously characterized global nitrogen regulator in S. coelicolor, positively regulated the transcription of nasA via specific binding to a cis-element similar but different from the previously characterized consensus sequence. This finding will certainly facilitate the better understanding about both the functional scope and the mechanism of action of GlnR in regulating nitrogen metabolism in S. coelicolor. (C) 2009 Elsevier Inc. All rights reserved.
著者Wang J, Zhao GP
期刊名稱Biochemical and Biophysical Research Communications
出版年份2009
月份8
日期14
卷號386
期次1
出版社Elsevier
頁次77 - 81
國際標準期刊號0006-291X
電子國際標準期刊號1090-2104
語言英式英語
關鍵詞GlnR; nasA; Nitrate reductase; Streptomyces coelicolor
Web of Science 學科類別Biochemistry & Molecular Biology; BIOCHEMISTRY & MOLECULAR BIOLOGY; Biophysics; BIOPHYSICS

上次更新時間 2020-17-11 於 00:53