Ultrasound screening for fetal structural abnormalities performed by trained midwives in the second trimester in a low-risk population - an appraisal
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AbstractObjective. To determine the performance of trained midwives in second trimester ultrasound screening for fetal structural abnormalities in a low-risk population. Design. Retrospective study. Setting. University Department of Obstetrics and Gynecology. Population. About 13,882 women with singleton pregnancies. Methods. The findings of routine second trimester anomaly scan performed by midwives were reviewed. Reasons for referral to maternal fetal medicine (MFM) specialists for further assessment were analyzed. Main outcome measures. The detection, false positive and false alarm rates for fetal anomalies. Results. One hundred and eighty-nine pregnancies with unknown outcome were excluded from the final analysis. Overall, 617 (4.51%) women were referred to MFM specialists for further assessment, of which 470 (70.2%) were for soft markers alone and 147 (23.8%) for suspected fetal structural abnormalities. In these 13,693 fetuses with known outcome, malformed fetuses were present in 185, a prevalence of 1.35%. Of these, 115 were detected during the second trimester scan and two were detected in the third trimester. The remaining 68 malformed fetuses, most of which had minor anomalies, were identified after birth. The detection rate for a malformed fetus in second trimester scan was 62.2% (115/185) (95% CI 55.2-69.2). There were four cases of false positives and 33 cases of false alarm. Conclusions. Experienced midwives with proper training can detect the majority of major structural abnormalities. Continuous audit and quality control plays a significant role in optimizing the fetal structural examination.
All Author(s) ListChen M, Leung TY, Sahota DS, Fung TY, Chan LW, Law LW, Chau MC, Lao THT, Lau TK
Journal nameActa Obstetricia et Gynecologica Scandinavica
Volume Number88
Issue Number6
PublisherWiley: 12 months
Pages713 - 719
LanguagesEnglish-United Kingdom
Keywordsfetal structural abnormalities; midwife; second trimester; Ultrasound screening
Web of Science Subject CategoriesObstetrics & Gynecology; OBSTETRICS & GYNECOLOGY

Last updated on 2020-10-07 at 02:16