Fossa Trochanterica of the Proximal Femur in Rabbits: An Anatomic Structure for Potential Misinterpretation on Magnetic Resonance Images
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摘要Background: Magnetic resonance imaging (MRI) has been increasingly used as an investigational tool for assessing the structure and function of animal skeletal disease models. However, to date, MRI tomographic knowledge of laboratory animal skeletal anatomy and pathology remains limited. Purpose: To demonstrate that fossa trochanterica of the proximal femur in rabbits can potentially be misinterpreted as a bone lesion on MR images. Material and Methods: Twenty 28-30-week-old male New Zealand white rabbits were used in the study. Corticosteroid-induced osteonecrosis induction was carried out with a combined administration of lipopolysaccharide and methylprednisolone. In this animal model, it is known that osteonecrosis commonly occurs in the proximal femur. MRI at 1.5T was performed before osteonecrosis induction, and at 1 and 2 weeks post-osteonecrosis induction. For anatomical imaging of the proximal femur, coronal sectional images were obtained to align the femoral head, neck, and proximal shaft in a single plane. Volumetric computed tomography (CT) comprised continuous axial acquisitions through the bilateral hip joints and femurs and was performed on one age- and sex-matched New Zealand white rabbit to correlate MRI anatomical findings. Results: In 30% of the acquired normal data sets, a low-signal area surrounded by high-signal bone marrow was observed slightly distal to the femoral head and medial to the third trochanter. This dark, low-signal area resembled an osteonecrosis lesion on MR images. Volumetric CT clarified that the low MR signal was due to the deep fossa trochanterica structure in the rabbit proximal femur. Conclusion: Improved understanding of the cross-sectional anatomy of the fossa trochanterica in the rabbit proximal femur will prevent misinterpretation as a bone lesion on MR images.
著者Wang HH, Wang YXJ, Sheng H, Zhang G, Qin L, Ahuja A, Teng LS
期刊名稱Acta Radiologica
出版年份2009
月份1
日期1
卷號50
期次2
出版社SAGE Publications (UK and US)
頁次212 - 216
國際標準期刊號0284-1851
電子國際標準期刊號1600-0455
語言英式英語
關鍵詞Computed tomography; femur; fossa trochanterica; magnetic resonance imaging; rabbit
Web of Science 學科類別Radiology, Nuclear Medicine & Medical Imaging; RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

上次更新時間 2021-26-01 於 00:59