A pilot MRI study of organ specific hemosiderosis and functional correlation in Chinese patients with myelodysplasia and aplastic anemia with raised ferritin levels
Publication in refereed journal

香港中文大學研究人員

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摘要We performed MRI and endocrine assessment in 27 adult Chinese patients with severe aplastic anemia (SAA) and myelodysplasia (MDS). Despite high ferritin levels, cardiac hemosiderosis and heart failure was not common, and were not concordant in most cases. However, significant correlation was found between cardiac T2/T2* MRI assessment, ejection fraction and ferritin levels. Furthermore, there was a high incidence subclinical pancreatic abnormality that was related to liver MRI T2* readings. Hence, chelating agents may still have a role to improve organ function. Prospective data with serial functional and imaging monitoring is needed. Copyright (C) 2008 John Wiley & Sons, Ltd.
著者Au WY, Lam WWM, Chu WWC, Tam S, Wong WK, Chan H, Law MF, Liu HSY, Liang R
期刊名稱Hematological Oncology
出版年份2008
月份12
日期1
卷號26
期次4
出版社Wiley: 12 months
頁次225 - 228
國際標準期刊號0278-0232
語言英式英語
關鍵詞aplastic anemia; hemosiderosis; myelodysplasia
Web of Science 學科類別Hematology; HEMATOLOGY; Oncology; ONCOLOGY

上次更新時間 2020-27-11 於 01:26