Engineering of pharmaceutical materials: An industrial perspective
Publication in refereed journal

香港中文大學研究人員

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摘要Crystal engineering provides a rational approach to solving formulation, processing and product performance problems. This review discusses how the concept of crystal engineering can be judiciously utilized to manipulate the solid-state properties of drugs and excipients for successful pharmaceutical formulation and process development. Existing and emerging manufacturing as well as co-processing technologies being applied in the pharmaceutical industry are also presented together with selected examples of crystal form design, crystal form selection and crystal modifications for illustration purposes. (C) 2007 Wiley-Liss, Inc. and the American Pharmacists Association.
著者Chow K, Tong HHY, Lum S, Chow AHL
期刊名稱Journal of Pharmaceutical Sciences
出版年份2008
月份8
日期1
卷號97
期次8
出版社Elsevier
頁次2855 - 2877
國際標準期刊號0022-3549
電子國際標準期刊號1520-6017
語言英式英語
關鍵詞crystal engineering; crystallization; formulation; particle size; pharmaceutical manufacturing; polymorphism; preformulation; selection of salt forms
Web of Science 學科類別Chemistry; Chemistry, Medicinal; CHEMISTRY, MEDICINAL; Chemistry, Multidisciplinary; CHEMISTRY, MULTIDISCIPLINARY; Pharmacology & Pharmacy; PHARMACOLOGY & PHARMACY

上次更新時間 2020-25-09 於 01:30