Postmortem MRI changes of the brains of the rats of different ages
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AbstractBrain degenerative changes were studied in the rats of different ages after cervical dislocation by T-2 MRI and histology. Appearance of dark spots in the T-2 images increased with increased duration after death. Quantitative analysis of the density of these spots revealed that the neonatal (1 week) and the old (9 months) animals had accelerated degenerative changes when compared with the young adult (1 month). The degenerative changes correlated with the accumulation of vacuoles or spaces in the brain tissue histologically. This study pointed out not only brain degenerative changes after death were associated with age, it also revealed that the MRI T-2 evaluations could be used as a way in postmortem investigation.
All Author(s) ListXu J, Zou Y, Zhang LH, Wai MSM, Kung HF
Journal nameInternational Journal of Neuroscience
Volume Number118
Issue Number7
PublisherTaylor & Francis: STM, Behavioural Science and Public Health Titles
Pages1039 - 1050
LanguagesEnglish-United Kingdom
Keywordsage; brain; degeneration; postmortem; T-2 MRI
Web of Science Subject CategoriesNeurosciences; NEUROSCIENCES; Neurosciences & Neurology

Last updated on 2020-26-11 at 00:49