Beneficial effect of phosphatidylcholine supplementation in alleviation of hypomania and insomnia in a Chinese bipolar hypomanic boy and a possible explanation to the effect at the genetic level
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AbstractIntroduction: Recent studies indicated that supplementation of phosphatidylcholine has been found to be beneficial for psychiatric diseases and Diacylglycerol Kinase, Eta (DGKH) protein was involved in regulating the metabolism of phosphatidic acid and diacylglycerol. This study reported a case of a 16-year-old Chinese boy with bipolar hypomania symptoms receiving supplementation of phosphatidylcholine, and a genetic study of a risk variant of DGKH gene was performed in an attempt to provide an explanation for the potential beneficial effect of phosphatidylcholine supplementation.
All Author(s) ListRao ST, Lam MHB, Wing YK, Yim LCL, Chu WCW, Yeung VSY, Waye MMY
Journal nameSpringerplus
Detailed descriptionTo ORKTS: doi: 10.1186/s40064-015-1002-y
Year2015
Month5
Day20
Volume Number4
PublisherSpringerOpen
ISSN2193-1801
LanguagesEnglish-United Kingdom
KeywordsBipolar hypomania; Diacylglycerol kinase eta (DGKH); Metabolism of diacylglycerol; Phosphatidylcholine supplementation; Susceptibility polymorphism
Web of Science Subject CategoriesMultidisciplinary Sciences; Science & Technology - Other Topics

Last updated on 2020-05-08 at 03:06