Fibroblast Growth Factor 21 Prevents Atherosclerosis by Suppression of Hepatic Sterol Regulatory Element-Binding Protein-2 and Induction of Adiponectin in Mice
Publication in refereed journal

Times Cited
Web of Science145WOS source URL (as at 24/06/2021) Click here for the latest count
Altmetrics Information

Other information
AbstractBackground-Fibroblast growth factor 21 (FGF21) is a metabolic hormone with pleiotropic effects on glucose and lipid metabolism and insulin sensitivity. It acts as a key downstream target of both peroxisome proliferator-activated receptor a and., the agonists of which have been used for lipid lowering and insulin sensitization, respectively. However, the role of FGF21 in the cardiovascular system remains elusive.
All Author(s) ListLin ZF, Pan XB, Wu F, Ye DW, Zhang Y, Wang Y, Jin LG, Lian QZ, Huang Y, Ding H, Triggle C, Wang K, Li XK, Xu AM
Journal nameCirculation
Detailed descriptionTo ORKTS: doi: 10.1161/CIRCULATIONAHA.115.015308
Volume Number131
Issue Number21
PublisherAmerican Heart Association
Pages1861 - 1871
LanguagesEnglish-United Kingdom
Keywordsadipokines; atherosclerosis; fibroblast growth factor 21; hormones
Web of Science Subject CategoriesCardiac & Cardiovascular Systems; Cardiovascular System & Cardiology; Peripheral Vascular Disease

Last updated on 2021-25-06 at 00:11