Noncardiac Comorbidities in Heart Failure With Preserved Ejection Fraction - A Commonly Ignored Fact
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AbstractIt has been well described that many patients with heart failure (HF) have a normal left ventricular ejection fraction. This entity has been termed "heart failure with preserved ejection fraction (HFPEF)". Significant advances have been made in understanding the clinical characteristics of HFPEF over the past 2 decades on the basis of large HF registries and randomized clinical trials. However, most multicenter clinical trials that investigated medical therapies in HFPEF have yielded disappointing results. HFPEF being a clinical syndrome involving multiple organ systems may be a potential explanation for treatment failure. In this review we discuss the prevalence of noncardiac comorbidities in HFPEF patients as well as their effect on the prognosis of HFPEF.
All Author(s) ListLiu M, Fang F, Yu CM
Journal nameCirculation Journal
Year2015
Month5
Day1
Volume Number79
Issue Number5
PublisherUnknown
Pages954 - 959
ISSN1346-9843
eISSN1347-4820
LanguagesEnglish-United Kingdom
KeywordsDiastolic dysfunction; Ejection fraction; Heart failure; Morbidity
Web of Science Subject CategoriesCardiac & Cardiovascular Systems; Cardiovascular System & Cardiology

Last updated on 2021-13-01 at 00:13