Heat Shock 70-kDa Protein 5 (Hspa5) Is Essential for Pronephros Formation by Mediating Retinoic Acid Signaling
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摘要Background: The function of Hspa5 in early embryonic development is not well understood. Results: Hspa5 is involved in mediating retinoic acid signaling and is required for pronephros. Conclusion: Hspa5 is essential for pronephros formation by mediating retinoic acid signaling. Significance: This is the first report on the cross-talk between physiological ER stress and transduction of retinoic acid signaling.
著者Shi WL, Xu G, Wang CD, Sperber SM, Chen YL, Zhou Q, Deng Y, Zhao H
期刊名稱Journal of Biological Chemistry
出版年份2015
月份1
日期2
卷號290
期次1
出版社American Society for Biochemistry and Molecular Biology
頁次577 - 589
國際標準期刊號0021-9258
電子國際標準期刊號1083-351X
語言英式英語
關鍵詞Development; Embryo; Endoplasmic Reticulum Stress (ER Stress); Kidney; Retinoic Acid; Xenopus
Web of Science 學科類別Biochemistry & Molecular Biology
