Whole-genome bisulfite sequencing of multiple individuals reveals complementary roles of promoter and gene body methylation in transcriptional regulation
Publication in refereed journal


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摘要Background: DNA methylation is an important type of epigenetic modification involved in gene regulation. Although strong DNA methylation at promoters is widely recognized to be associated with transcriptional repression, many aspects of DNA methylation remain not fully understood, including the quantitative relationships between DNA methylation and expression levels, and the individual roles of promoter and gene body methylation.
著者Lou SK, Lee HM, Qin H, Li JW, Gao ZB, Liu X, Chan LL, Lam VKL, So WY, Wang Y, Lok S, Wang J, Ma RCW, Tsui SKW, Chan JCN, Chan TF, Yip KY
期刊名稱Genome Biology
詳細描述To ORKTS: My postdoctoral associate, Shaoke Lou, is one of the co-first authors of the publicaiton.

I am one of the co-corresponding authors of thi
出版年份2014
月份1
日期1
卷號15
期次7
出版社BioMed Central
國際標準期刊號1474-760X
電子國際標準期刊號1474-760X
語言英式英語
Web of Science 學科類別Biotechnology & Applied Microbiology; Genetics & Heredity

上次更新時間 2021-18-01 於 00:10