Cramer-Rao Bound for Intravoxel Incoherent Motion Diffusion Weighted Imaging Fitting
Refereed conference paper presented and published in conference proceedings


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摘要The precision of parameter estimation for Intravoxel Incoherent Motion Diffusion Weighted Imaging (IVIM-DWI) was investigated by examining their Cramer-Rao bounds (CRBs) under the presence of Rician noise. Monte Carlo (MC) simulation was also conducted to validate the CRB results. The estimation uncertainties of true diffusion coefficient (D) and perfusion fraction (f(0)) could reach 3.89% and 11.65% respectively with typical parameter values at a moderate signal-to-noise ratio (SNR) of 40. However, to estimate pseudo diffusion coefficient (D*) within 10% uncertainty requires SNR>122. The results also showed that the estimation precision of each parameter is not only dependent on SNR but also their true values, while this mutual dependency is complicated. Under some particular cases, estimation uncertainty for certain parameters might be smaller than 5% at a moderate SNR of 40. However, the simultaneous precise estimation for all three parameters is theoretically difficult and highly SNR demanding.
著者Zhang QW, Wang YX, Ma HT, Yuan J
會議名稱35th Annual International Conference of the IEEE-Engineering-in-Medicine-and-Biology-Society (EMBC)
會議開始日03.07.2013
會議完結日07.07.2013
會議地點Osaka
會議國家/地區日本
期刊名稱Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society
詳細描述organized by IEEE, EMB, JSMBE,
出版年份2013
月份1
日期1
出版社IEEE
頁次511 - 514
電子國際標準書號978-1-4577-0216-7
國際標準期刊號1557-170X
語言英式英語
Web of Science 學科類別Engineering; Engineering, Biomedical; Engineering, Electrical & Electronic

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