Exposure to air pollutants and mortality in hypertensive patients according to demography: A 10 year case-crossover study
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AbstractThis study evaluated whether short term exposures to NO2, O-3, particulate matter <10 mm in diameter (PM10) were associated with higher risk of mortality. A total of 223,287 hypertensive patients attended public health-care services and newly prescribed at least 1 antihypertensive agent were followed-up for up to 5 years. A time-stratified, bi-directional case-crossover design was adopted. For all-cause mortality, significant positive associations were observed for NO2 and PM10 at lag 0-3 days per 10 mu g/m(3) increase in concentration (excess risks 1.187%-2.501%). Significant positive associations were found for O-3 at lag 1 and 2 days and the excess risks were 1.654% and 1.207%, respectively. We found similarly positive associations between these pollutants and respiratory disease mortality. These results were significant among those aged >= 65 years and in cold seasons only. Older hypertensive patients are susceptible to all-cause and respiratory disease-specific deaths from these air pollutants in cold weather. (C) 2014 Elsevier Ltd. All rights reserved.
All Author(s) ListWong MCS, Tam WWS, Wang HHX, Lao XQ, Zhang DD, Chan SWM, Kwan MWM, Fan CKM, Cheung CSK, Tong ELH, Cheung NT, Tse LA, Yu ITS
Journal nameEnvironmental Pollution
Volume Number192
Pages179 - 185
LanguagesEnglish-United Kingdom
KeywordsAir pollutants; Case-crossover; Hypertension; Mortality; Particulate matter
Web of Science Subject CategoriesEnvironmental Sciences; ENVIRONMENTAL SCIENCES; Environmental Sciences & Ecology

Last updated on 2021-19-02 at 23:55