K-mer natural vector and its application to the phylogenetic analysis of genetic sequences
Publication in refereed journal

香港中文大學研究人員

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摘要Based on the well-known k-mer model, we propose a k-mer natural vector model for representing a genetic sequence based on the numbers and distributions of k-mers in the sequence. We show that there exists a one-to-one correspondence between a genetic sequence and its associated k-mer natural vector. The k-mer natural vector method can be easily and quickly used to perform phylogenetic analysis of genetic sequences without requiring evolutionary models or human intervention. Whole or partial genomes can be handled more effective with our proposed method. It is applied to the phylogenetic analysis of genetic sequences, and the obtaining results fully demonstrate that the k-mer natural vector method is a very powerful tool for analysing and annotating genetic sequences and determining evolutionary relationships both in terms of accuracy and efficiency. (C) 2014 Elsevier B.V. All rights reserved.
著者Wen J, Chan RHF, Yau SC, He RL, Yau SST
期刊名稱Gene
出版年份2014
月份8
日期1
卷號546
期次1
出版社Elsevier
頁次25 - 34
國際標準期刊號0378-1119
電子國際標準期刊號1879-0038
語言英式英語
關鍵詞K-mer model; Natural vector; Phylogenetic analysis
Web of Science 學科類別Genetics & Heredity; GENETICS & HEREDITY

上次更新時間 2020-17-10 於 00:07